Saturday, October 17, 2015

10 Glutathione Benefits


10 Glutathione Benefits

Top 10 Benefits of Glutathione

1. Increase In Energy

Many people are fanatical about getting enough Beta Carotene, Vitamin C, and Vitamin E due to their powerful anti-oxidant properties. However, what they overlook is that without adequate levels of glutathione in the body, these vitamins are not effective, as they work hand in hand with it. Therefore, Glutathione increases the effectiveness of these minerals and vitamins, leaving you healthier, with better mental clarity, and ultimately more energy. 

2. Slows the Aging Process

Studies have shown that as we age, Glutathione levels drop. Therefore, in order to slow down the process, maintaining healthy levels is imperative especially in old age as it is the repair mechanism for the body structures necessary for energy production in every living cell in your body. Preventing and repairing cells damaged by oxidative stress, the leading cause of aging and age related problems. Further, low glutathione levels are also implicated in diseases associated with aging e.g. Parkinson’s, cataracts, and Alzheimer’s.

3. Improved Skin

One positive side effect from the supplementation of Glutathione is that the skin becomes lighter. This has led to the introduction of cosmetic products including soap for those who would wish to improve their skin color. While this skin lightening may not be consistent in all people, it has been demonstrated to be true in a high percentage of people.

4. Mitigates the Effects of Stress

Elevated Glutathione levels are responsible for reducing the effects of stressful episodes. This is because as the chief anti-oxidant, it works in conjunction with other vitamins and minerals thereby allowing the others to flourish in their roles. Reducing oxidative stress and other free radicals that increase during stressful episodes.

5. Reduces Joint and Muscle Discomfort

Whether in athletes or those who frequent the gym, optimum levels of this antioxidant guarantees reduced muscle and joint aches especially after intense workouts. As well as minimizing free radicals released from, muscle tears and extreme excursion.

6. Detoxification of the Liver and Cells

Since alcohol is responsible for diminished Glutathione levels in the liver, it is prudent to work heartily to maintain healthy levels especially if you regularly consume it. It is also crucial in getting rid of pollutants, contributing to the liver’s well being. Allowing healthy liver function and natural regeneration of damaged liver cells.

7. Improved Mental Clarity and Focus

Since our brains can be severely hampered by the effects of certain fats and free radicals, Glutathione has been shown to mitigate the effects of this brain changing elements. Once optimal or normal levels of this super antioxidant have been restored in the body, many people report increased mental clarity. 

8. Strengthening of the Immune System

Numerous medical studies have shown that whenever people fall ill, their levels of Glutathione also fall. This phenomenon has been observed in severe illnesses like cancer, diabetes, and cardiovascular disease. The same also holds true for people battling other common ailments such as the flu or common cold. In maintaining high levels of this super antioxidant, your body is able to maintain a powerful immune system backed by strong cells. Viruses and bacteria intent on invading your body are severely hampered.

9. Improved Athletic Performance and Recovery

Undoubtedly, one of the most remarkable effects of Glutathione is to be found in the sporting world. Top athletes now acknowledge that maintaining high levels enables them to train longer, harder, and recover much faster.

10. Improved Sleep

Healthy levels of this super antioxidant in the body are associated with improved quality sleep devoid of interruptions.

Friday, October 16, 2015

Cellgevity-Your Body's Miracle Molecule

Help Your Body Protect Itself

Cellgevity is Max’s premiere formula and features our proprietary RiboCeine™ technology, a special blend of D-Ribose and L-Cysteine, combined with an all-star collection of 12 complementary ingredients to more effectively enhance the function of glutathione within your body.
          
Our bodies create glutathione to defend against violent attackers like free radicals, chemical toxins, heavy metals, and other influences that can negatively affect our overall health. Glutathione also works to regulate, recycle, and repair other antioxidants within your body. As we age, the levels of this important molecule are depleted by every-day trauma including physical and mental stress, poor diet, and lack of sleep.

Give your body the advanced Glutathione support it deserves

  • Advanced RiboCeine™ formula featuring 12 supplemental ingredients
  • Provides protection from oxidative stress and free radicals
  • Supports cellular function and health
Look, Feel, and Live to the Max with Cellgevity’s Advanced RiboCeine™ Technology combined with these potent antioxidants and helpful enzymes.

                        Product Details:

RiboCeine™

RiboCeine™ is a patented breakthrough nutrient compound clinically proven to deliver the key precursor nutrient, cysteine, to the cell. RiboCeine™ enables the cell to produce optimal levels of glutathione. Backed by 25 years of research and 20 published and peer-reviewed scientific studies funded by the National Institutes of Health and other scientific institutions, RiboCeine™ was proven to significantly outperform all other means of glutathione enhancement, against which it was tested.
 

Alpha Lipoic Acid

Alpha Lipoic Acid is a powerful endogenous antioxidant known to combat various forms of oxidative stress and to recycle other antioxidants. Together with glutathione, they protect the fat and water portions of the cells from different types of free radicals.
 

Broccoli Seed Extract

Broccoli Seed Extract (sulforaphane glucosinolate) acts as a catalyst to boost antioxidant activity for as much as three days. Protects against DNA damaging electrophiles and helps cells neutralize toxins and carcinogens so they are eliminated from cells. It also helps to raise and replenish glutathione levels and induces the antioxidant enzymes used in the Phase II detoxification pathway.
 

Turmeric Root Extract

Turmeric Root Extract (Curcumin) is a potent antioxidant that fights free radicals and is known to reduce inflammation. Curcumin also induces Phase II enzymes that support the glutathione detoxification pathway
 

Resveratrol

Resveratrol is an antioxidant found in high concentrations in grape skin, also found in wines, with higher concentrations in red wine verse white wine. Resveratrol is thought to account in a large part for the so called 'French Paradox'. The French Paradox - the findings that the rate of coronary heart disease in France was observed to be lower than in other countries with a similar risk factor - has been attributed to the consumption of red wine. Resveratrol is an antioxidant known to have cardio-protective properties.

Grape Seed Extract

Grape Seed proanthocyanidines have antioxidant activity, as well as anti-inflammatory properties.

Quercetin

Quercetin is a supporting flavonoid antioxidant that scavenges free radicals that can damage cells.

Milk Thistle

Milk Thistle (silymarin) is a powerful antioxidant used to support a healthy liver by removing harmful toxins and heavy metals that are stored in the liver.

Vitamin C

Vitamin C is an exogenous antioxidant that is considered a network antioxidant and known to support the immune system.

Selenomethionine

Selenomethionine (Selenium) is the essential catalytic component of the enzyme glutathione peroxidase (GPx) and is absolutely required for its function. Selenium is needed as selenomethionine for the antioxidant enzyme, glutathione peroxidase. The glutathione peroxidase enzyme is responsible for the detoxification of lipid peroxides, and glutathione is absolutely required to regenerate this enzyme.

Cordyceps

Cordyceps has been used as a Chinese medicine for centuries and has been valued for its activity in restoring energy, increasing stamina, promoting longevity and improving quality of life.

Black Pepper

Black Pepper (BioPerine) assists in the absorption of selenomethionine, vitamin C and curcumin (turmeric root).

Aloe Extract

Aloe Extract has the most bio-active content of acemannan, the active ingredient in aloe. Aloe is known to support the immune system and has antioxidant functions.
 
TESTIMONIALS
 
People from all walks of life benefit from Cellgevity. Here are some of their stories.          

Dr. Gordon Crozier

Integrative Medicine I find Cellgevity to be incredibly useful in my day to day life. Not only do I have more energy to do my work, it plays a very supportive role in helping my body remove toxins.

Lewey Adams

Cellgevity User After going on Cellgevity I feel better than I have in years. I was not only able to drive 90 miles to work and hit the ground running, I am also to enjoy a game of basketball with my daughter.

Max GXL- Glutathione Accelerator: Fast Fifty Promotion World Wide Promotion

Max GXL- Glutathione Accelerator: Fast Fifty Promotion World Wide Promotion: Fast Fifty Promotion World Wide Promotion   Earn an extra $50 U.S. when new Associates who enroll and purchase a minimum 100 PV...

Fast Fifty Promotion World Wide Promotion


Fast Fifty Promotion
World Wide Promotion
 
Earn an extra $50 U.S. when new Associates who enroll and purchase a minimum 100 PV, earn their first commission check.
 
All Associates who sponsor 10 new Associates during promotional period, who earn the Fast Fifty Bonus will earn an Apple Watch (valued at $400). 
    
Dates:
 
1. Sponsor new Associates who enroll and purchase 100 PV between September 1, 2015 and October 31, 2015.
 
2. New Associates can earn their first commission check between September 1, 2015 and December 31, 2015.
 
Details:
 
1. Promotional Dates:
September 1, 2015 through October 31, 2015 new Max Associates who enroll and purchase a minimum of 100 PV during these dates are eligible for the Fast Fifty Bonus.
 
2. New Associates have from September 1 through December 31, 2015 to earn their first commission check.
 
3. Associates who have enrolled before September 1, 2015 are eligible to win an Apple Watch ($400) value or equivalent priced prize, for sponsoring a minimum of 10 new Associates who earn their first commission check and the Fast Fifty bonus.
 
Questions and Answers:
 
1. As a new Associate do I have to purchase 100 PV each month to qualify for Fast Fifty Promotion?
 
Answer: You must be qualified to earn commissions, which requires each Associate to purchase a minimum of 100 PV to receive a weekly or monthly commission check.
 
2. If I sponsor new Associates each month can I receive a Fast Fifty Bonus each month?
 
Answer: No the Fast Fifty Bonus is paid only on your first commission check.
 
3. As a sponsoring Associate can I sponsor 2 new Associates and they sponsor 8 more new Associates during the promotional period, can I qualify for the Apple Watch?
       
Answer: No you must personally sponsor 10 new Associates who qualify and earn the Fast Fifty
Bonus.
 
4. As an existing Associate can I qualify for the Apple Watch if I sponsor 10 new Associates in Nov. and Dec., who earn the Fast Fifty Bonus during Nov and December 2015?
 
Answer: No, you must sponsor 10 new Associates during the promotional period, Sept. and Oct.
5. Can I earn the Fast Fifty Promotional Bonus on weekly commissions earned?
 
Answer: Yes, you will be paid the Fast Fifty Bonus on your first commission check, either weekly or monthly.

Friday, October 9, 2015

Max International is proud to announce the official opening of our 10th Market – Hong Kong!

 
For MAX DIRECT ORDERS IN HONG KONG AREA

 

Max International is proud to announce the official opening of our 10th Market – Hong Kong!


Max International’s continuing vision is to bring our ground-breaking health supplements, skin care and weight loss systems to all corners of the globe.  Today, Max is proud to announce the launch of our newest opening in Hong Kong.

Max Hong Kong is now officially opened!

Known as the “Pearl of the Orient,” Hong Kong is a major economic force in the Asia Pacific region and is renowned for its highly ranked economic freedom, quality of life, and financial competitiveness.  Hong Kong has positioned itself as very welcoming to the MLM industry and is ripe for an influx of new network marketing opportunities.  We already have several Chinese-speaking Associates who have established contacts in Hong Kong, so we expect immediate and explosive growth in this exciting new market.

Our official opening meeting will be held on Saturday, November 2.  This grand opening will be the kick-off event for the commencement of business in Hong Kong.  Max President Jim Stevralia will lead the festivities and will welcome special guests Scott Momii and Scott Nagasawa.
Hong Kong will open with MaxOne™, Max N-Fuze™, MaxATP™ and the Visible Solutions™ Skin Care system.   Max Hong Kong will have enrollment packs similar to those available in our other markets.  Please check the Max International Hong Kong website for details and additional information.

The Hong Kong office opens Monday, November 4th and will support Max Associates in both Cantonese and English languages.  The office hours are Monday to Friday 11:00 AM to 7:00 PM and Saturday 10:00 AM to 3:00 PM.  To learn more about the details of this exciting new market, including how to sign up new Associates in Hong Kong, look for our FAQ Business Guide which will be hosted on the Hong Kong business site max.com/hk.

Max is excited to expand once again into a region where our products and business opportunity are poised to make real differences in people’s lives.  Join us as we welcome Hong Kong to the Max family of nations!

 
Max Hong Kong Business Guide FAQ

Why is Hong Kong such an important new market for Max?
Hong Kong represents a tremendous opportunity for Max Associates because of its strong economics and favorable business history. As a bustling and thriving city that welcomes and recognizes many international MLM companies, Hong Kong serves as the perfect location for Max International’s newest market.  With the large number of Chinese speaking Associates in our existing markets who already have contacts in Hong Kong, we see this as a significant new market for Max and our Associates.

How will the business function and Associates be supported in Hong Kong?
Our business plan for Hong Kong provides you with all the services necessary to operate your business effectively and to leverage assistance (in both English and Chinese) from our Max Customer Care representatives. We will ship products to you and your Associates from our facility, or you can pick up your orders from our office in Tsim Sha Tsui (Kowloon).

How do I sign up my prospects?
Signing up prospects is identical to the process used in all of our existing markets. It is important that each prospect must present a valid government issued Hong Kong identification number in order to enroll as a Max Associate.  Prospects can enroll simply by entering the URL www.max.com/hk/yourID number to enroll from the Hong Kong website. Alternatively, you can enroll new Associates from your Max4U Associate replicated website under the Hong Kong flag tab, using your Associate ID Number and your Personal Identification Number (PIN).  Upon enrolling, they will receive a Max identification number.
Also, you can download an Associate application or a Preferred Customer application and fax them to the office to be processed. After enrolling, new Associates need to go into their Virtual Office to sign up for commission payments via direct deposit and step-by-step instructions on how to setup direct deposit. An Associate’s commissions will continue to accrue until this process is completed.

What is the Enrollment Security PIN and how is it used to enroll?
When a new prospect residing in Hong Kong enrolls online they are required to submit the enrollment pin of their sponsor. This secondary security measure is in place to safeguard your business.  We encourage all Sponsors to always meet any new prospects in person to develop a productive business relationship before you provide them with your enrollment security PIN.
Log onto your Virtual Office to find your enrollment PIN.  When the Hong Kong site goes live you’ll be able to download an Associate application or a Preferred Customer application click and fax the application to our Hong Kong office.

How do I receive my commissions?
The Secondary Bonus (Fast Track commissions) is paid weekly every Wednesday, and the Primary Bonus (Monthly commissions) is paid on the 15th of the following month. Commissions are paid via our online system called MyMaxPay. This program gives you total control and flexibility in how you receive your commissions. Here are some key benefits:
  • You can access your commission balances online, anytime, anywhere.
  • You can immediately transfer commissions to your bank account.
  • You can transfer funds to a prepaid Max International Visa card for greater convenience.
  • You can access your account through your smart phone to review balances or to make transfers.
  • You can purchase product directly through your MyMaxPay accounts.
See MyMaxPay.com for more information or call your local Customer Care for details.

How do I pay for my orders or application?
When ordering online you can pay by credit card (MasterCard or Visa). When ordering at our Hong Kong office you can pay with credit card (MasterCard or Visa) or cash.
If you do not have a credit card, you may pay by bank transfer.  Deposit the correct amount to Max’s HSBC account (Account Number 023-202344-838), then fax a copy of the stamped deposit slip and your order and/or application to our Hong Kong office (Fax Number: 852 3547 0232). Scanned copies of the deposit slip and application can be emailed to hksupport@max.com.  Please note any bank transfer fees are for your account.

Do Max products have an official Hong Kong Registration Number?
Currently, health supplements sold in Hong Kong are not subject to official registration and approval through the local health department. However, the department does provide very specific guidelines for the importers and manufacturers of health supplements. Specifically, the importers and manufacturers are provided detailed requirements to ensure their health supplements comply with the safety and quality standards of the ministry.
To ensure the good reputation of Max International and the products made available to the public in Hong Kong, Max has employed local third-party regulation assistance to provide thorough guidance on prohibited substances as well as specifications on the limits and types of the ingredients that can be included. Max will only sell products acceptable under the department’s guidelines.

What products will Max start with in Hong Kong and what packs will be available?
The market will open with three of Max’s flagship products, MaxOne™, Max N-Fuze™    and MaxATP™ as well as our extraordinary line of skin care products, Visible Solutions™.   Max Hong Kong will have enrollment packs similar to those available in our other markets for the products we sell.  Please check the Hong Kong website for details.

What online services and marketing materials will be available for Hong Kong?
Hong Kong uses the same online platform used in all our other markets. www.max.com/hk is the general market site for the launch. Please refer to the Hong Kong website for important information such as corporate announcements, downloads, press releases and quick links. Max4U Associate replicated websites are also available for a subscription.

What is the address and contact information for the Hong Kong Office?
Our office is located at:
Unit 6, 6/F Chevalier House
45-51 Chatham Road South,
Tsim Sha Tsui, Kowloon
Hong Kong
Phone: (852) 3547 0274 for English line or
(852) 3547 0298 for Chinese line
Fax: (852) 3547 0232
Email: hksupport@max.com

What are the office hours and language for support at the Max office?
The Hong Kong office will support Max Associates in both Cantonese and English.
Our office hours are:
Monday to Friday – 11:00 AM to 7:00 PM
Saturday – 10:00 AM to 3:00 PM

How can I best take advantage of the Hong Kong Market?
The management team at Max always recommends you that counsel with your upline to strategize about how you can take full advantage of any market.  Your team works best when you can establish clear direction and goals.

Over time, Hong Kong will have open meetings just like all our other markets that you will be able to leverage. In this age of digital communication you can make effective use of technology (Skype, Facebook, email, etc.) to build in foreign countries without having to ignore your home market and team.

Max is extremely excited to partner with you as you build your teams in Hong Kong.
 

Wednesday, September 2, 2015

Cellgevity: Max International's Advanced RiboCeine Technology

Cellgevity 4-week box set

Safe for
Professional Athletic Use

Cellgevity Decorative Stripe Banned Substance Control Group logo certifying product is safe for professional athletes
*Specially formulated to contain no contaminants or banned substances as certified by the Banned Substance Control Group (BSCG) giving professional athletes worldwide the confidence to use Max products within competition.
 
Empower Your Health and Wellness

Help Your Body Protect Itself

Cellgevity is Max’s premiere formula and features our proprietary RiboCeine™ technology, a special blend of D-Ribose and L-Cysteine, combined with an all-star collection of 12 complementary ingredients to more effectively enhance the function of glutathione within your body.
Our bodies create glutathione to defend against violent attackers like free radicals, chemical toxins, heavy metals, and other influences that can negatively affect our overall health. Glutathione also works to regulate, recycle, and repair other antioxidants within your body. As we age, the levels of this important molecule are depleted by every-day trauma including physical and mental stress, poor diet, and lack of sleep.

Give your body the advanced Glutathione support it deserves

  • Advanced RiboCeine™ formula featuring 12 supplemental ingredients
  • Provides protection from oxidative stress and free radicals
  • Supports cellular function and health
 
PRODUCT OVERVIEW
 
Look, Feel, and Live to the Max with Cellgevity’s Advanced RiboCeine™ Technology combined with these potent antioxidants and helpful enzymes.
 

RiboCeine™

RiboCeine™ is a patented breakthrough nutrient compound clinically proven to deliver the key precursor nutrient, cysteine, to the cell. RiboCeine™ enables the cell to produce optimal levels of glutathione. Backed by 25 years of research and 20 published and peer-reviewed scientific studies funded by the National Institutes of Health and other scientific institutions, RiboCeine™ was proven to significantly outperform all other means of glutathione enhancement, against which it was tested.

Alpha Lipoic Acid

Alpha Lipoic Acid is a powerful endogenous antioxidant known to combat various forms of oxidative stress and to recycle other antioxidants. Together with glutathione, they protect the fat and water portions of the cells from different types of free radicals.

Broccoli Seed Extract

Broccoli Seed Extract (sulforaphane glucosinolate) acts as a catalyst to boost antioxidant activity for as much as three days. Protects against DNA damaging electrophiles and helps cells neutralize toxins and carcinogens so they are eliminated from cells. It also helps to raise and replenish glutathione levels and induces the antioxidant enzymes used in the Phase II detoxification pathway.

Turmeric Root Extract

Turmeric Root Extract (Curcumin) is a potent antioxidant that fights free radicals and is known to reduce inflammation. Curcumin also induces Phase II enzymes that support the glutathione detoxification pathway.

Resveratrol

Resveratrol is an antioxidant found in high concentrations in grape skin, also found in wines, with higher concentrations in red wine verse white wine. Resveratrol is thought to account in a large part for the so called 'French Paradox'. The French Paradox - the findings that the rate of coronary heart disease in France was observed to be lower than in other countries with a similar risk factor - has been attributed to the consumption of red wine. Resveratrol is an antioxidant known to have cardio-protective properties.

Grape Seed Extract

Grape Seed proanthocyanidines have antioxidant activity, as well as anti-inflammatory properties.

Quercetin

Quercetin is a supporting flavonoid antioxidant that scavenges free radicals that can damage cells.

Milk Thistle

Milk Thistle (silymarin) is a powerful antioxidant used to support a healthy liver by removing harmful toxins and heavy metals that are stored in the liver.

Vitamin C

Vitamin C is an exogenous antioxidant that is considered a network antioxidant and known to support the immune system.

Selenomethionine

Selenomethionine (Selenium) is the essential catalytic component of the enzyme glutathione peroxidase (GPx) and is absolutely required for its function. Selenium is needed as selenomethionine for the antioxidant enzyme, glutathione peroxidase. The glutathione peroxidase enzyme is responsible for the detoxification of lipid peroxides, and glutathione is absolutely required to regenerate this enzyme.

Cordyceps

Cordyceps has been used as a Chinese medicine for centuries and has been valued for its activity in restoring energy, increasing stamina, promoting longevity and improving quality of life.

Black Pepper

Black Pepper (BioPerine) assists in the absorption of selenomethionine, vitamin C and curcumin (turmeric root).

Aloe Extract

Aloe Extract has the most bio-active content of acemannan, the active ingredient in aloe. Aloe is known to support the immune system and has antioxidant functions.
        

People from all walks of life benefit from Cellgevity. Here are some of their stories.

Dr. Gordon Crozier

Integrative Medicine
I find Cellgevity to be incredibly useful in my day to day life. Not only do I have more energy to do my work, it plays a very supportive role in helping my body remove toxins.

Lewey Adams

Cellgevity User After going on Cellgevity I feel better than I have in years. I was not only able to drive 90 miles to work and hit the ground running, I am also to enjoy a game of basketball with my daughter.
                        

 

Sound Science Provides Breakthrough Products

RiboCeine™

Max’s Answer to Supplementation for Effective Glutathione Production
Because glutathione (GSH) is the primary protector and detoxifier of the cell, scientists and medical professionals have looked for ways to effectively raise and support glutathione levels for years. However, glutathione cannot be effectively absorbed through the intestinal tract; so it must be made by the body itself.

The body makes (synthesizes) glutathione from three amino acids: cysteine, glycine, and glutamic acid. While glycine and glutamic acid are readily available within the body, cysteine is more difficult to make and much must be supplemented through diet.

Until recently, N-acetyl cysteine (NAC) was the only dietary supplement available to enhance the body's supply of cysteine to promote the production of glutathione. Now, Max International is proud to present RiboCeine, a critical breakthrough in cysteine supplementation for optimal glutathione production.       
RiboCeine is Proven and Patented Technology
RiboCeine is a unique molecule that combines ribose and cysteine, nutrients that are naturally occurring in humans, to more effectively deliver cysteine directly to our cells. This groundbreaking compound enters the bloodstream and delivers cysteine, as well as ribose, to the cells to stimulate the production of glutathione, the body's master antioxidant, as well as ATP, our cells’ natural fuel and source of energy.

RiboCeine has significantly outperformed other means of glutathione enhancement against which it has been tested, and has been the subject of twenty published, peer-reviewed scientific studies that were funded by the National Institutes of Health and other scientific funding agencies. RiboCeine was developed over years of research by the well-known research scientist and medicinal chemist, Herbert T. Nagasawa, Ph.D., and this technology is now patented in the United States.

Independent Studies on the Effects of Ribose-Cysteine

NOTE: The following links take you away from this page to 3rd party research sites.

1. Jurkowska, H.; Uchacz, T.; Roberts, J.; Wrobel, M. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation Amino Acids, 2 April 2010
2. Walker, R.B.; Everette J.D., Comparative Reaction Rates of Various Antioxidants with ABTS Radical Cation. J. Agric Food Chem, 2009, 57, 1156-1161.
3. Heman-Ackah, S.E.; Juhn, S.K.; Huang, T.C.; Wiedmann, T.S. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation. Otolaryngology-Head and Neck Surgery, 2010, 143, 429-434.
4. Oz, H.S.; Chen, T.S.; Nagasawa, H., Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model. Translational Research, 2007, 150(2), 122-129.
5. Lucas Slitt, A.M.; Dominick, P.K.; Roberts, J.C.; Cohen, S.D. Effect of Ribose Cysteine Pretreatment on Hepatic and Renal Acetaminophen Metabolite Formation and Glutathione Depletion. Basic Clin. Pharmacol. Toxicol., 2005, 96 (6), 487-94.
6. Lenarczyk, M.; Ueno, A.; Vannais, D.B.; Kraemer, S.; Kronenberg, A.; Roberts, J.C.; Tatsumi, K.; Hei, T.K.; Waldren, C.A. The "Pro-drug" RibCys Decreases the Mutagenicity of High-LET Radiation in Cultured Mammalian Cells. Radiation Research, 2003, 160, 579-583.
7. Wilmore, B.H.; Cassidy, P.B.; Warters, R.L.; Roberts, J.C. Thiazolidine Prodrugs as Protective Agents against y-Radiation-Induced Toxicity and Mutagenesis in V79 Cells. J. Med. Chem., 2001, 44(16), 2661-2666.
8. Lucus, A.M.; Henning G.; Dominick, P.K.; Whiteley, H.E.; Roberts, J.C.; Cohen, S.D. Ribose Cysteine Protects Against Acetaminophen-Induced Hepatic and Renal Toxicity. Toxicologic Pathology, 2000, 28(5), 697-704.
9.Roberts, J.C.; Phaneuf, H.L.; Dominick, P.K.; Wilmore, B.H.; Cassidy, P.B. Biodistribution of [35S] - Cysteine and Cysteine Prodrugs: Potential Impact on Chemoprotection Strategies. J. Labelled Cpd. Radiopharm., 1999, 42, 485-495.
10. Roberts, J.C.; Phaneuf, H.L.; Szakacs, J.G.; Zera, R.T.; Lamb, J.G.; Franklin, M.R. Differential Chemoprotection against Acetaminophen-Induced Hepatotoxicity by Latentiated L-Cysteines. Chem. Res. Toxicol., 1998, 11, 1274-1282.
11. Bantseev, V.; Bhardwaj, R.; Rathbun, W.; Nagasawa, H.T.; Trevithick, J.R. Antioxidants and Cataract: (Cataract Induction in Space Environment and Application to Terrestrial Aging Cataract). Biochem. Mol. Bio. Intl., 1997, 42, 1189-1197.
12. Roberts, J.C.; Koch, K.E.; Detrick, S.R.; Warters, R.L.; Lubec G. Thiazolidine Prodrugs of Cysteamine and Cysteine as Radioprotective Agents. Radiation Research, 1995, 143, 203-213.
13. Carroll, M.P.; Zera, R.T.; Roberts, J.C.; Schlafmann, S.E.; Feeny, D.A.; Johnston, G.R.; West, M.A.; Bubrick, M.P. Efficacy of Radioprotective Agents in Preventing Small and Large Bowel Radiation Injury. Dis. Colon Rectum, 1995, 38(7), 716-722.
14. Roberts, J.C.;Francetic, D.J.; Zera, R.T. Chemoprotection against Cyclophosphamide-Induced Urotoxicity: Comparison of Nine Thiol Protective Agents. AntiCancer Research, 1994, 14, 389-396.
15. Rowe, J.K.; Zera, R.T.; Madoff, R.D.; Fink, A.S.; Roberts, J.C.; Johnston, G.R.; Freeney, D.A.;Young, H.L.; Bubrick, M.P. Protective Effect of RibCys Following High-Dose Irradiation of the Rectosigmoid. Dis. Colon Rectum, 1993, 36(7), 681-687.
16. Roberts, J.C.; Charyulu, R. L.; Zera, R.T.; Nagasawa, H.T. Protection Against Acetaminophen Hepatotoxicity by Ribose-Cysteine (RibCys). Pharmacology & Toxicology, 1992, 70, 281-285.
17. Roberts, J.C.; Francetic, D.J. - Mechanisms of Chemoprotection by RibCys, a Thiazolidine Prodrug of L-cysteine. Med. Chem. Res., 1991, 1, 213-219.
18. Roberts, J.C.; Francetic, D.J. Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys. Toxicology Letters, 1991, 59, 245-251.
19. Roberts, J.C.; Francetic, D.J.; Zera, R.T. L-cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity. Cancer Chemotherapy and Pharmacology 1991, 28, 166-170.
20. Roberts, J.C.; Nagasawa, H.T.; Zera, R.T.; Fricke, R.F.; Goon, D.J. W. Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(polyhydroxyalky)-and 2-(Polyacetoxyalky)-Thiazolidine-4(R)-Carboxylic Acids. J. Med Chem. 1987, 30, 1891-1896.

Our Science

Our Science


 
Max is committed to producing and delivering the best possible glutathione enhancing products in the world. We know how important it is that high quality health and wellness products be based on proven scientific research. Max International is determined to lead the wellness and nutritional industry in delivering quality products based on science and science-based proprietary formulations.
Most companies start with a motive for profit, ours started with the purpose of empowerment.
Thanks to the efforts of medicinal chemist Dr. Herbert T. Nagasawa and other experts in scientific research and development, Max International has developed groundbreaking advances in glutathione enhancing products.

The Max Difference

HOW ARE WE DIFFERENT? 

Max International is dedicated to improving everyday lives. This commitment can be seen in everything we do, from our superior products to the charity events we organize around the world. This isn’t some newfound mission; it’s been our focus from Day 1.
Thanks to the efforts of medicinal chemist Dr. Herbert T. Nagasawa and other experts in scientific research and development, Max International has developed groundbreaking advances in glutathione enhancing products.
 
When our founder, Steven Scott, began developing world-class solutions to the ongoing health crises we all face, he started by tapping leading scientists and employees. Our team is committed to safe and effective products that supplement glutathione, the body’s master antioxidant and a vital protector against free radicals. This dedication has earned Max a U.S. patent for RiboCeine™ one of the core components to a variety of our products. We invite you to learn more about our Executive Team, who help guide and drive our initiatives.

Glutathione and its Useful Benefits

Glutathione and its Useful Benefits

Read More : Glutathione
Since healthy DNA is needed to prevent replication of mutated cells, we need to protect it from free radicals by the aid of Antioxidants.

Antioxidant Neutralizes Free Radical
Antioxidants have “extra” electrons that they can give to free radicals. By doing that, it eliminates its harmful effect. Antioxidants are the body’s defense against destructive free radicals which causes aging, sickness and disease.
What Type of Antioxidant Do We Need???

Exogenous Antioxidant
If we will take Exogenous Antioxidant like the famous Vitamin C and Vitamin E, we are protecting our cells from being damaged, but it can not repair or restore damaged cells. It only shields our body from incoming free radicals. In other words, exogenous antioxidant has no ability to neutralize or stop mutated cells to grow erratically. It is important exogenous antioxidants like Vitamin C and Vitamin E can not do their job adequately to protect our body against disease.

Endogenous Antioxidant Glutathione GSH
 
Glutathione GSH plays a very important role in DNA. Healthy DNA is essential to prevent mutated cells from replicating itself which will lead to Cancer.
 
What Science have proven is that when you have high levels of glutathione gsh, you will be protected from free radical damage, all other Antioxidants like Vitamin C and Vitamin E can do their job efficiently, your vital organs will function better and you will have better functioning immune system. Generally speaking, having high levels of Glutathione GSH means having a healthier body.

Suggested Reading:

Saturday, August 22, 2015

WHAT IS GLUTATHIONE (GSH)?



What Glutathione (GSH) is and
how it affects your immune health


WHAT IS GLUTATHIONE (GSH)?


Glutathione molecule Glutathione (or GSH) is the body’s own master antioxidant discovered way back in 1889. However, it was only about 30 years ago that the scientists began to understand its functions and discovered how to raise its levels.

GSH is a small protein molecule composed of 3 amino acids: cysteine, glutamate, and glycine called GSH precursors or building blocks.


GSH is produced out of these three precursors in every cell of the human body and performs many important roles, such as:
  • Regulation of cell growth and division
    For cells to grow and divide they go through several very complex stages. Glutathione reduces the oxides, such as hydrogen peroxide, inside the cell that would otherwise prevent cell division and growth.

  • DNA synthesis and repair (synthesis - reproduction/creation of a new copy)
    Glutathione protects the DNA from oxidative stress during cell division which allows for DNA synthesis (division). When the DNA is mutated by a free radical stealing an electron from the DNA, glutathione repairs the mutated DNA by giving up an electron to the DNA (replacing the DNA’s missing electron).

  • Protein synthesis
    Glutathione maintains our proteins in their proper form. Its sulfur atom reacts with unnatural sulfur-sulfur bonds in proteins, breaking them and allowing the proper pairings to form.

  • Amino acid transport (transport - movement into, out of, within a cell, or between cells, by means of some agent such as a transporter)
    Glutathione is predominately located in the cell, whereas a major fraction of the cellular y-glutamyl transpeptidase (glutathione enzyme) is on the external surface of cell membranes. This means intracellular glutathione is translocated out of many cells – glutathione moves substances, such as amino acids, in and out of the cell.
  • Enzyme catalysis
    Glutathione provides the mechanism by which many enzymes are changed (reduced, transformed or changed from one state to another state). Glutathione is the bridge (catalysis) in the chemical reaction between some enzymes.

  • Enzyme activation
    The highly reactive sulfide bond in glutathione wakes up or activates enzymes so that they carry out their function or are moved from one phase to the next.

  • Metabolism of toxins (metabolism or biotransformation – breaking down, activating or transforming)
    In the liver, the enzyme glutathione S-transferase takes the sulfur from glutathione and attaches it to toxic molecules, this makes the toxin more water soluble (it is diluted in water easily). Once a toxin is water soluble, it is transported to the body's elimination systems and is excreted from the body.

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  • Metabolism of carcinogens
    Glutathione enzymes transform carcinogens, through chemical reaction, to unreactive and non-genotoxic compounds that can be eliminated without causing damage to the cell or DNA.

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  • Metabolism of xenobiotics (xenobiotics - chemical components (drugs and poisons) foreign to the body)
    Glutathione interacts with foreign chemicals (primarily, it is a scavenger of harmful xenobiotics that have been oxidized) compounds to neutralize and break them down, then eliminate them from the body.

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  • Conjugation to heavy metals (conjugation – joining with and transforming by becoming part of)
    Glutathione joins with heavy metals to neutralize them and eliminate them from the body.

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  • Conjugation to xenobiotics
    In some instances, depending on the state of the xenobiotic, glutathione joins with it instead of metabolizing it.

  • Enhancement of systemic immune function
    The immune system works best if the lymphoid cells have properly balanced glutathione. The cloning of T-cells consumes large quantities of cysteine. Macrophages (type of white blood cells), which are only present in sufficient quintiles when there is sufficient glutathione, provide the cysteine for the T-cell cloning. Glutathione regulates the binding, internalization, degradation and T-cell proliferation by increasing, as much as two times, the number of binding cellular receptors. More receptors equates to more T-cells being produced simultaneously (multiple T-cell cloning). Cellular GSH also affects the growth and replication of T-cells through growth stimulating cytokines.

  • Enhancement of humoral immune function
    The role of glutathione in the humoral response is that it protects the cells taking part in the humoral response all along this complex process.
    A quick synapsis of the humoral immune response: “humoral” means circulating in the bloodstream. This is an immune response (chiefly against bacterial invasion) that is mediated by B cells and involves the transformation of B cells into plasma cells that produce and secrete antibodies to a specific antigen.
    The process in a nutshell: macrophages engulf and digest the invading pathogen. The digested pieces activate helper T cells which in turn activate the proliferation of B cells that are programed for the specific invading pathogen.

  • Resistance to UV radiation
    Glutathione detoxifies reactive oxygen radicals created by radiation which reduces the damage to the cell. Glutathione also interacts covalently and noncovalently (neutralizes the reactivity in several ways) with parts of the cell that keep the cell from triggering apoptosis (cell death).

  • Decreases radiation damage
    The action of glutathione in decreasing the damage from radiation is the same as in resistance to UV radiation above.

  • Decreases free radical damage
    The crucial cysteine molecule is the key to the protection afforded by glutathione. Its sulfur atom scavenges destructive molecules (peroxides and free radicals) converting them to harmless compounds, such as water.

  • Decreases oxyradical damage
    Glutathione detoxifies reactive oxygen radicals by giving them an electron which effectively neutralizes them, or glutathione joins with the oxyradical which again neutralizes it.
  • Metabolizing of hydrogen peroxide (H2O2)
    Glutathione biotransforms hydrogen peroxide by turning it into harmless water.

  • Recycling of other antioxidants (master antioxidant role)
    Glutathione recycles oxidized lipoic acid, vitamin C and E by restoring them to an active state, mostly by donating the electrons that they used in metabolizing (neutralizing) free radicals. So, instead of having this army of antioxidants flushed out, they are recycled by glutathione and sent back out to work.

  • Storage and transport of cysteine
    Glutathione is a tripeptide made up of amino acids CYSTEINE, glycine and glutamate. Glutathione provides and determines the amount and availability of neuronal cysteine.

  • Regulation of homocysteine
    The methionine cycle and the transsulfuration sequence compose the mechanisms for homocysteine metabolism. Transsulfuration sequence requires large quantities of cysteine. It is suspected that the rapid turnover of glutathione in the liver, kidneys, small intestine and pancreas accounts for the metabolism of homocysteine in these organs. Homocysteine metabolism also involves multiple enzymes. Excessive homocysteine is a known contributing factor of hardening of arteries (atherosclerosis).

  • Participation in nutrient metabolism

  • and more

  • WHY IS GLUTATHIONE IMPORTANT?


    The immune system and detoxification system cannot function without GSH. In his book "Glutathione. Your body's most powerful protector" Dr. Jimmy Gutman says "Glutathione modulation is an essential part of staying young, active and healthy." He also states - "By keeping our intracellular GSH levels up we also keep our immune system on the ball and fully armed".
    In the immune system the protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them.
    GSH has been clinically researched and proven to optimize your immune system, maximize the function of antioxidants, support your detoxification process at the cellular level, increase your energy levels and increase your strength and endurance.

    Medical symbol As of April 2012, Pubmed.gov (the government's depository for research articles in medical and biomedical fields) lists 100,775 medical articles mentioning GSH. This is a tremendous amount of research and energy that the medical profession has put into understanding the role of GSH in our lives. Optimizing your GSH levels benefits everyone, from children to those in their golden years, from the infirm to the elite athlete.

    Do not underappreciate the profound meaning of this statement - raising your GSH level is CLINICALLY PROVEN TO BE BENEFICIAL for a very wide array of health concerns.
    The research continues at an amazing pace. If you want to know what research has been done for your particular condition go to PubMed and simply type in your condition. It will list the abstracts of related articles. If you want to know what influence GSH plays in your condition, type in "glutathione and your condition", then hit Search. I was amazed at what has been researched and is not common knowledge.

    WHAT DOES GLUTATHIONE DO IN OUR BODIES?



    Antioxidant - GSH is the body’s master Antioxidant, our bodies depend on GSH for the removal of toxins and GSH is at the heart of all immune functions. Other antioxidants in our body depend on GSH to function properly.
    Detoxification - GSH detoxifies a large number of pollutants by binding to carcinogens, heavy metals, herbicides, pesticides and radiation by forming a soluble compound with the toxin that can then be excreted through the urine or bile.
    Immune system - Healthy growth and activity of immune cells depends on the availability of GSH. The protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them.
    Increased Energy - Our energy levels are a result of many factors - everything from the biochemical reactions taking place within our cells, to muscle function and even your sense of well-being. GSH enables the mitochondria of a cell to remain fully charged, enhancing muscle strength and endurance. Clinical trials have shown that lowering GSH in the mitochondria results in cell death.
    Repair - Our body is constantly under attack from free radicals, some from external sources and some generated in our own body. Free radicals attack the nearest stable molecule, "stealing" its electron. A molecule that loses an electron then becomes a free radical itself and attacks the next nearest stable molecule, this begins a chain reaction. Once the reaction is started it can cascade through hundreds of molecules. As this occurs over and over again the cell eventually dies or mutates. GSH performs a vital role in repairing the damaged DNA by replacing the missing electron. Normal to elevated GSH keeps the repair of our cells at a maximum and reduces the number of cell mutations that would occur otherwise.

    Glutathione exists in reduced (GSH) and oxidized (GSSG) states. In healthy cells and tissue, more than 90% of the total Glutathione is in the reduced form (GSH) and less than 10% exists in the oxidized form (GSSG). An increased GSSG-to-GSH ratio is considered indicative of oxidative stress. The ratio of reduced Glutathione to oxidized Glutathione within cells is often used scientifically as a measure of cellular toxicity.


    Watch Dr. Gutman explain the role of GSH
    in immune health:

     



    To know more: http://www.immunehealthscience.com/glutathione.html

    Sunday, August 2, 2015

    Cellgevity™ 1 Mo (120 Capsules)

    Cellgevity™ 1 Mo (120 Capsules) - Cellgevity 1Mo V2 EN US 

    Supplement Facts
    Aloe Extract

    Aloe Extract

    Aloe Extract has the most bio-active content of acemannan, the active ingredient in aloe. Aloe is known to support the immune system and has antioxidant functions. Read more »
    Black Pepper

     

     

     

     

     Black Pepper

    Black Pepper (BioPerine) assists in the absorption of selenomethionine, vitamin C and curcumin (turmeric root). Read more »
    Cordyceps

     

     

     

     

     

     

     

     

    Cordyceps

    Cordyceps has been used as a Chinese medicine for centuries and has been valued for its activity in restoring energy, increasing stamina, promoting longevity and improving quality of life. Read more »
    Selenomethionine

     

     

     

     

     

    Selenomethionine

    Selenomethionine (Selenium) is the essential catalytic component of the enzyme glutathione peroxidase (GPx) and is absolutely required for its function. Selenium is needed as selenomethionine for t... Read more »
    B Vitamins

     

     

     

     

     

     

    B Vitamins

    B Vitamins Description Read more »
    Milk Thistle

     

     

     

     

     

     

     

     

     

    Milk Thistle

    Milk Thistle (silymarin) is a powerful antioxidant used to support a healthy liver by removing harmful toxins and heavy metals that are stored in the liver. Read more »
    Quercetin

     

     

     

     

     

     

    Quercetin

    Quercetin is a supporting flavonoid antioxidant that scavenges free radicals that can damage cells. Read more »
    Grape Seed Extract

     

     

     

     

     

     

     

    Grape Seed Extract

    Grape Seed proanthocyanidines have antioxidant activity, as well as anti-inflammatory properties. Read more »
    Resveratrol

     

     

     

     

     

     

     

     

    Resveratrol

    Resveratrol is an antioxidant found in high concentrations in grape skin, also found in wines, with higher concentrations in red wine verse white wine. Resveratrol is thought to account in a large ... Read more »
    Turmeric Root Extract

     

     

     

     

     

     

    Turmeric Root Extract

    Turmeric Root Extract (Curcumin) is a potent antioxidant that fights free radicals and is known to reduce inflammation. Curcumin also induces Phase II enzymes that support the glutathione detoxific... Read more »
    Broccoli Seed Extract

     

     

     

     

     

    Broccoli Seed Extract

    Broccoli Seed Extract (sulforaphane glucosinolate) acts as a catalyst to boost antioxidant activity for as much as three days. Protects against DNA damaging electrophiles and helps cells neutralize... Read more »
    Alpha Lipoic Acid

     

     

     

     

     

     

    Alpha Lipoic Acid

    Alpha Lipoic Acid is a powerful endogenous antioxidant known to combat various forms of oxidative stress and to recycle other antioxidants. Together with glutathione, they protect the fat and water... Read more »
    Riboceine

     

     

     

     

     

     

    Riboceine

    RiboCeine™ is a breakthrough nutrient compound clinically proven to deliver the key precursor nutrient, cysteine, to the cell. RiboCeine enables the cell to produce optimal levels of glutathione. B... Read more »